Loaʻa i ka laina kelepona nā pono o ka paʻa a me ka hana kiʻekiʻe
ʻO nā laina kelepona nā moʻomeheu o nā cell i loaʻa mai nā mea ola, e like me ke kanaka, holoholona, mea kanu, a me ka bacteria.Ua ulu lākou i loko o ka hale hana a hiki ke hoʻohana ʻia no nā kumu like ʻole, e like me ke aʻo ʻana i nā hopena o kekahi mau lāʻau lapaʻau, ka noiʻi ʻana i nā maʻi genetic, a i ʻole ka hana ʻana i nā lāʻau lapaʻau.Hoʻohana mau ʻia nā laina kelepona, ʻo ia hoʻi, hiki iā lākou ke puʻunaue mau loa a hiki ke hoʻohana ʻia i nā hoʻokolohua no nā manawa lōʻihi.
Laina Kelepona Make ole
ʻO ka laina kelepona he pūʻulu o nā pūnaewele i hana ʻia mai hoʻokahi cell a e hoʻohua mau loa me ka ʻole o ka hoʻololi ʻana i kona ʻano genetic.ʻO nā laina kelepona make ʻole he mau laina kelepona hiki ke puʻunaue mau loa, a ua hana ʻia e loaʻa nā kiʻekiʻe kiʻekiʻe o ka telomerase, he enzyme e kōkua i nā cell e noho ola.Hoʻohana mau ʻia nā laina kelepona ola ʻole i ka noiʻi biomedical a no ka hana ʻana i nā protein therapeutic a me nā molekole ʻē aʻe.ʻO nā laʻana o nā laina kelepona make ʻole, ʻo ia nā pūnaewele HeLa, nā pūnaewele CHO, a me nā pūnaewele COS-7.
Ell Line Development
ʻO ka hoʻomohala ʻana i ka laina hua ka hana o ka hana ʻana i nā ʻano mea kanu hou mai kahi hua.ʻO kēia kaʻina hana maʻamau e pili ana i ka hoʻohua koho ʻana o ʻelua a ʻoi aku paha nā ʻano mea kanu i mea e hana ai i kahi ʻano hou me nā ʻano i makemake ʻia.Hiki ke hana ma ka lima a i ʻole ma o ka hoʻohana ʻana i nā ʻenehana loea genetic hou.ʻO ka pahuhopu o ka hoʻomohala ʻana i ka laina hua, ʻo ia ka hana ʻana i nā ʻano mea kanu i hui maikaʻi ʻia o nā ʻano, e like me ke kūpaʻa ʻana i ka maʻi, ka hua kiʻekiʻe, ka ʻono maikaʻi, a me ka hoʻomaikaʻi ʻana i ka meaʻai.Hiki ke hoʻohana ʻia kēia kaʻina hana no ka hana ʻana i nā ʻano hou o nā pūhui lāʻau lapaʻau a i ʻole nā huahana ʻē aʻe i loaʻa mai nā mea kanu.
Nā Kelepona Laina Germ
ʻO nā pūnaewele laina Germ kekahi mau mea hoʻohua i kuleana no ka hāʻawi ʻana i ka ʻike genetic mai kekahi hanauna a i kekahi.ʻO ia nā pūnaewele nona ke kuleana no ka hoʻohua ʻana, a ʻike pinepine ʻia lākou i loko o nā ʻano hānau o nā holoholona a me nā mea kanu.I loko o ke kanaka, loaʻa nā cell line germ i loko o nā ovaries a me nā hōʻike.Hāʻawi lākou i nā gametes, a i ʻole nā pūnaewele wahine, aia ka hapalua o ka ʻike genetic e pono ai no ka hana hou ʻana.
